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1,1,3,3-Tetramethylguanidine As A Nonaqueous Solvent Cas 80-70-6
DESCRIPTION
Tetramethylguanidine is an organic compound with the formula HNC(N(CH3)2)2. This colourless liquid is a strong base, as judged by the high pKa of it conjugate acid.It was originally prepared from tetramethylthiourea via S-methylation and amination, but alternative methods start from cyanogen iodide.
Specification
| CAS No. | 80-70-6 |
| MF | C5H13N3 |
| EINECS No. | 201-302-7 |
| Place of Origin | China |
| Density | 0.9g/cm3 |
| Water solubility | miscible |
| Refractive index | 1.445 |
| Flash point | 60°C |
| Vapour Pressure | 2.09mmHg at 25°C |
| Appearance | Liquid |
| Mp | -30℃ |
| Bp | 163.2°C at 760 mmHg |
| Molecular Weight | 115.1768 |
| Sample | Availiable |
| Safety Description | S16:; S26:; S36/37/39:; S45:; |
| Risk Codes | R10:; R20/22:; R34:; |
USES
Tetramethylguanidine is mainly used as a strong, non-nucleophilic base for alkylations, often as a substitute for the more expensive DBU and DBN. Since it is highly water-soluble, it is easily removed from mixtures in organic solvents. It is also used as a base-catalyst in the production of polyurethane.
